Keyshia Cole

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Robin Thicke

Episode number: 1

Overview: We're starting off the new year with Robin Thicke and his Sex Therapy...like father like son. Comedian Jo Koy, comedian Christina Pazsitzky and comedian Guy Branum are on the panel.

Mary J. Blige

Episode number: 2

Overview: We're getting deep with Mary J. Blige and her new album, Stronger With Each Tear, word. Comedian Chris Hardwick, comedians Randy and Jason Sklar.

Holly Madison

Episode number: 3

Overview: We're getting deep with Mary J. Blige and her new album, Stronger With Each Tear, word. Comedian Chris Hardwick, comedians Randy and Jason Sklar.

Joel David Moore

Episode number: 4

Overview: Holly Madison is dropping on by her old E! family today...we've missed her, too. Comedian Donnel Rawlings, comedian Heather McDonald and comedian Gary Valentine.

Giuliana & Bill Rancic

Episode number: 5

Overview: Word on the street is Giuliana and Bill Rancic are trying to have a baby. What're the odds that we'll get any sort of big announcement? Comedian Brad Wollack, comedian Natasha Leggero and comedian Matt Braunger.

Aisha Tyler

Episode number: 6

Overview: We welcome back the very funny Aisha Tyler, from the new show Archer. Comedian Jo Koy, comedian Loni Love and comedian Josh Wolf.

Amy Brenneman

Episode number: 7

Overview: Amy Brenneman of Private Practice stops by, perhaps with some doctorly advice. Comedian John Caparulo, comedian Jen Kirkman and comedian Dan Levy.

Snooki, Pauly D and The Situation

Episode number: 8

Overview: Fist pumps all around for Jersey Shore's Snooki, Pauly D and The Situation. Comedian Chris Franjola, comedian Whitney Cummings and TV personality Ross Mathews.

David Arquette

Episode number: 9

Overview: David Arquette is back and telling us all about his new play The Female of the Species and the Golden Globes! Comedians Michelle Collins and Randy and Jason Sklar

Adrianne Palicki

Episode number: 10

Overview: Clear eyes, full hearts, can't lose with Legion's Adrianne Palicki (aka FNL's Tyra). Comedian Chris Hardwick, actress-comedian Arden Myrin and comedian Eric Price.

Kaley Cuoco

Episode number: 11

Overview: Who wouldn't be stoked that Kaley Cuoco from the megapopular Big Bang Theory is here? Comedian Heather McDonald, TV personality Ross Mathews and comedian Lavell Crawford.

James Van Der Beek

Episode number: 12

Overview: James Van Der Beek is in the new movie Formosa Betrayed and popping up all over TV—even here! E!'s own Michael Yo, comedian Sarah Colonna and comedian Guy Branum.

Katharine McPhee

Episode number: 13

Jill Scott

Episode number: 14

Dax Shepard

Episode number: 15

Staff Book Club

Episode number: 16

Camila Alves

Episode number: 17

Andy Whitfield

Episode number: 18

Shorty Rossi

Episode number: 19

Julie Benz

Episode number: 20

Ozzy Osbourne

Episode number: 21

Amanda Seyfried

Episode number: 22

Dave Salmoni

Episode number: 23

Overview: We're beyond pleased to welcome back our animal guy Dave Salmoni and his new animal friends. Comedian Jo Koy, comedian Christina Pazsitzky and comedian Mo Mandel.

Channing Tatum

Episode number: 24

Kate Flannery

Episode number: 25

Overview: We get down to business with The Office's Kate Flannery. Comedian Loni Love, comedian Dan Levy and comedian Whitney Cummings.

Jackie Collins

Episode number: 26

Overview: Things get really scandalous when author Jackie Collins stops by with her new book, Poor Little Bitch Girl. Comedian Chris Hardwick, comedian Jen Kirkman and comedian Jo Koy.

Lisa Edelstein

Episode number: 27

Overview: Lisa Edelstein from House is back again...Wait, so who's running Princeton Plainsboro? Comedian Josh Wolf, comedian Heather McDonald and comedian Ryan Stout.

Eli Roth

Episode number: 28

Keshia Knight Pulliam

Episode number: 29

Overview: House of Payne's Keshia Knight Pulliam is one hard working lady; Dr. Huxtable would be so proud. Comedian Loni Love, TV personality Rove McManus and comedian Michelle Collins

Danica Patrick

Episode number: 30

Overview: We're pretty thrilled that Danica Patrick makes a pit stop over at Chelsea Lately today. Comedian Josh Wolf, comedian Whitney Cummings and comedian Jo Koy.

Radha Mitchell

Episode number: 31

Overview: Things might get wild with Radha Mitchell star of the new thrilling horror movie The Crazies. Comedian John Caparulo, comedian Bill Bellamy and actress-comedian Arden Myrin.

Parker Posey

Episode number: 32

Overview: The Chelsea Lately cast do a Kardashian skit. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.

Sean William Scott

Episode number: 33

Overview: From the new movie Cop Out we've got Seann William Scott in our custody today. Comedian Chris Hardwick and Comedians Randy and Jason Sklar.

Kendra & Hank Baskett

Episode number: 34

Overview: Kendra and Hank Baskett are here to tell us all about the spellbinding new season of Kendra. E!'s own Michael Yo, comedian Sarah Colonna and comedian Jo Koy.

Single Staffers, Handler Edition

Episode number: 35

Overview: Please enjoy a very special Handler Edition of Single Staffers. Comedian Matt Bruanger, comedian Heather McDonald and comedian Moshe Kasher.

Gabourey Sidibe

Episode number: 36

Overview: From Precious, the Academy Award-nominated Gabourey Sidibe is here. TV personality Ross Mathews, comedian Christina Pazsitzky and comedian Guy Branum.

Kevin McKidd

Episode number: 37

Overview: Someone got some time away from the O.R., Grey's Anatomy's Kevin McKidd is here. Comedian John Caparulo, comedian Arden Myrin and comedian Chris Franjola.

Chelsea Chelsea Bang Bang

Episode number: 38

Overview: Chelsea Chelsea Bang Bang is in stores now...You're welcome, everyone. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.

Amy Ryan

Episode number: 39

Overview: Chelsea Chelsea Bang Bang is in stores now...You're welcome, everyone. Comedian Brad Wollack, comedian Natasha Leggero and comedian Ben Gleib.

Pretty Wild Cast

Episode number: 40

Overview: Alexis Neiers, Gabrielle Neiers and Tess Taylor are here from their aptly titled new series on E! Pretty Wild. Comedian Brad Wollack, comedian Dan Levy and comedian Josh Wolf.

Shenae Grimes

Episode number: 41

Overview: 90210's Shenae Grimes is here to give us the deets on all things West Beverly. Comedian Bobby Lee, comedian T.J. Miller and comedian Whitney Cummings.

Rachael Harris

Episode number: 42

Overview: From the highly anticipated Diary of a Wimpy Kid, the purely entertaining Rachael Harris is here. Comedian Jo Koy, comedian Loni Love and comedian Josh Wolf.

Avril Lavigne

Episode number: 43

Overview: We catch up with Avril Lavigne, who sings "Alice," the title song from Tim Burton's Alice in Wonderland. Comedian Sarah Colonna, comedian/TV host Rove McManus and comedian Mo Mandel.

Duane "Dog" Chapman

Episode number: 44

Overview: We're so thrilled to welcome the author of Where Mercy Is Shown, Mercy Is Given, Dog the Bounty Hunter. Comedian John Caparulo, comedian Heather McDonald and TV personality Ross Mathews.

Kelly Cutrone

Episode number: 45

Scott Wolf

Episode number: 46

Crispin Glover

Episode number: 47

Blake Shelton

Episode number: 48

Ludacris

Episode number: 49

Overview: Ludacris is back with his new album Battle of the Sexes and this time he's bringing drinks. Comedian Ben Gleib, comedian Natasha Leggero and comedian Guy Branum.

Johnny Weir

Episode number: 50

Overview: Johnny Weir is here, and unfortunately our show is not "on ice" this week. Comedian Jo Koy, comedian Lil JJ and comedian Sarah Colonna.

Erykah Badu

Episode number: 51

Justin Bieber

Episode number: 52

Overview: Chuy Bravo wrote a book, Little Nuggets of Wisdom, and he's here to share them. This, BTW, is all 100 percent for real, for real, girl. Comedian Heather McDonald, comedians Randy & Jason Sklar.

Jennifer Love Hewitt

Episode number: 53

Overview: Author of The Day I Shot Cupid, Jennifer Love Hewitt is here. Comedian Brad Wollack, E!'s own Michael Yo and Comedian Mo Mandel,

Ed Asner

Episode number: 54

Overview: Find out how spunky Chelsea can really be when TV Icon and star of Up Ed Asner stops by. Comedian Josh Wolf, comedian Loni Love and comedian Wil Anderson.

Blake MyCoskie

Episode number: 55

Overview: Things get real philanthropic up in here with Tom's Shoes founder Blake Mycoskie. Comedian Greg Behrendt, comedian Jen Kirkman and comedian Matt Braunger.

Taraji P. Henson

Episode number: 56

Overview: From the highly anticipated movie Date Night, the Academy Award-nominated Taraji P. Henson is here. Comedian Chris Franjola, comedian Chris Hardwick, TV personality Ross Mathews.

Tiny & Toya

Episode number: 57

Overview: From BET's Tiny & Toya, BFFs Tiny & Toya are here. Comedian Whitney Cummings, actress Cloris Leachman and TV personality Ross Mathews.

Our 500th Episode

Episode number: 58

Overview: Come celebrate a real milestone at Chelsea Lately—tonight's our 500th episode! Comedian Jo Koy, comedian Sarah Colonna and comedian Josh Wolf.

Dave Salmoni

Episode number: 59

Overview: Resident animal expert Dave Salmoni is back with some hopefully furry friends. Comedian Dan Levy, comedian Arden Myrin and comedian Lavell Crawford.

Erin Andrews & Maksim Chmerkovskiy

Episode number: 60

Overview: Dancing With the Stars' hottest couple Erin Andrews and Maksim Chmerkovskiy. Comedian John Caparulo, comedian Heather McDonald and comedian Donnell Rawlings.

Gretchen Wilson

Episode number: 61

Amy & Matt Roloff

Episode number: 62

Katie Cassidy

Episode number: 63

Ted Allen

Episode number: 64

Michael Weatherly

Episode number: 65

Jerry Weintraub

Episode number: 66

Jeffrey Dean Morgan

Episode number: 67

Brooke Shields

Episode number: 68

Molly Ringwald

Episode number: 69

Busy Philipps

Episode number: 70

Monica

Episode number: 71

Michael Lewis

Episode number: 72

Amanda Seyfried

Episode number: 73

Laura Bell Bundy

Episode number: 74

Asian Singles with Jo Koy

Episode number: 75

Carson Kressley

Episode number: 76

Bradley Whitford

Episode number: 77

Marisa Miller

Episode number: 78

Mary Lynn Rajskub

Episode number: 79

Damon Wayans

Episode number: 80

James Van Praagh

Episode number: 81

Judge Lately

Episode number: 82

Tim Roth

Episode number: 83

Zach Gilford

Episode number: 84

Snoop Dogg and Mike Epps

Episode number: 85

Justin Halpern

Episode number: 86

Overview: The man behind all things Shit My Dad Says, Justin Halpern is here. Comedian Bobby Lee, comedian Jen Kirkman and comedian Dov Davidoff.

Colin Hanks

Episode number: 87

Overview: Tonight we welcome Colin Hanks, one of The Good Guys from the new Fox drama. Comedian Heather McDonald, comedian Randy Sklar and musician Jeff Wild.

Clay Aiken

Episode number: 88

Overview: Clay Aiken is here, seriously, with his new CD Tried and True. Comedian Ben Gleib, comedian Loni Love and Comedian Gary Valentine.

Holly Madison

Episode number: 89

Overview: Holly Madison is back with her new show Holly's World. Comedian Chris Hardwick, comedian Guy Branum and actress-comedian Arden Myrin.

Stephen Moyer

Episode number: 90

Overview: True Blood is returning and Stephen Moyer is here, so get excited...or scared?! I'm not really sure. Comedian Jo Koy, comedian Eric Price and comedian Chris Franjola.

Denis Leary

Episode number: 91

Overview: Star of all things Rescue Me the hilarious Denis Leary is here. Comedian Steve Marmalstein, comedian Natasha Leggero and TV personality Ross Mathews.

Sarah McLachlan

Episode number: 92

Overview: We're getting a little Lilith tonight when Sarah McLachlan stops by and talks her new album, Laws of Illusion. Comedian Jo Koy, E!'s own Michael Yo and comedian Sarah Colonna.

Lil Jon

Episode number: 93

Overview: We're getting crunk with Lil Jon and his new album Crunk Rock…YEAAAAHHHH! Comedian John Caparulo, comedian Christina Pazsitzky and comedian Josh Wolf.

Roy Handler & Charley

Episode number: 94

Overview: Learn how to make cupcakes with Roy and Charley tonight. Comedian Brad Wollack, comedian Dan Levy and comedian Bobby Lee.

A.J. Khubani

Episode number: 95

Overview: Learn about the borderline amazing new As Seen on TV Products with A.J. Khubani. Comedian Chris Franjola, comedian Whitney Cummings and comedian Finesse Mitchell.

Mary McCormack

Episode number: 96

Overview: Star of In Plain Sight Mary McCormack graces us with her presence. Comedian Joe DeRosa, comedian Heather McDonald and comedian Josh Wolf.

Ron Artest

Episode number: 97

Overview: Comedian Matt Braunger, comedian Moshe Kasher and comedian Guy Branum. Lakers champ Ron Artest tries to get into Chelsea's pants and chats about his NBA win. Plus, hear about his budding music career!

Ashley Greene

Episode number: 98

Overview: Actress Ashley Greene on her new movie, "The Twilight Saga: Eclipse"; Round table discussion with comics Mo Mandel, Arden Myrin, and Ross Mathews.

T.I.

Episode number: 99

Overview: Rapper T.I. on his new album, "King Uncaged"; Round table discussion with comics Sarah Colonna, Jamie Kaler, and Josh Wolf.

Bryce Dallas Howard

Episode number: 100

Overview: From the most-anticipated movie in the country, Eclipse, Bryce Dallas Howard is here. Comedian Brad Wollack, comedian John Caparulo and comedian Christina Pazsitzky

Joe's Crab Shack

Episode number: 101

Overview: Check out Chuy as the new spokesperson for Joe's Crab Shack...You're welcome crabs. Comedian Bobby Lee, comedian Jo Koy and comedian Ben Gleib

Sam Trammell

Episode number: 102

Overview: True Blood's favorite shapeshifter Sam Trammell is back. Comedian Bobby Lee, comedian Jo Koy and comedian Ben Gleib

Claire Smith

Episode number: 103

Overview: Learn about the summer's best drinks with Belvedere's Claire Smith. Comedian Jason Sklar, comedian Natasha Leggero and comedian Gary Valentine

Pharrell

Episode number: 104

Overview: Pharrell does a lot, like producing the soundtrack and composing the score for Despicable Me. Comedian Jo Koy, comedian Whitney Cummings and TV personality Ross Mathews.

Kristin Cavallari

Episode number: 105

Overview: Kristin Cavallari is here and has all the info you're dying to know about the final season of The Hills. Comedian Chris Hardwick, comedian Heather McDonald and comedian Dov Davidoff

Dave Salmoni

Episode number: 106

Overview: Canadian animal trainer Dave Salmoni on his new show, "Savaged with Dave Salmoni"; Round table discussion with comics Jason Sklar, Natasha Leggero, and Gary Valentine.

Susan Sarandon

Episode number: 107

Overview: Actress Susan Sarandon on her upcoming reality ping-pong series; Round table discussion with comics Jo Koy, Ben Gleib, and Brad Wollack.

Anna Paquin

Episode number: 108

Overview: Sink your teeth into this: tonight we welcome Anna Paquin from HBO's True Blood. Rapper Lil John, rapper Big Boi and rapper Rick Ross.

Arsenio Hall

Episode number: 109

Overview: Dust off your fists, girls, because Arsenio Hall is in the house. Comedian Chris Franjola, comedian Christina Pazsitzky and TV personality Ross Mathews

Frank Grillo

Episode number: 110

Overview: Actor Frank Grillo on his show, "The Gates"; Round table discussion with comics Loni Love, Josh Wolf, and Greg Proops.

Kathy Griffin

Episode number: 111

Overview: Comedian Kathy Griffin on her show, "Kathy Griffin: My Life on the D-List"; Round table discussion with comics Jo Koy, Michael Yo, and Whitney Cummings.

Chicken Charlie

Episode number: 112

Overview: Fry cook Chicken Charlie discusses frying food; Round table discussion with comics Chris Hardwick, Heather McDonald, and Rove McManus.

Ron Livingston

Episode number: 113

Overview: Actor Ron Livingston on his new film, "Dinner with Schmucks"; Round table discussion with comics Ross Mathews, Sarah Colonna, Guy Branum.

Gabrielle Reece

Episode number: 114

Overview: Tonight's guest is volleyball pro Gabby Reece. At the Round Table: John Caparulo, Christina Pazsitzky, Matt Braunger.

Lisa Lampanelli

Episode number: 115

Overview: Tonight's guest is actress Lisa Lampanelli. At the Round Table: Brad Wollack, Jo Koy, James Van Praagh.

Fat Joe

Episode number: 116

Overview: Fat Joe returns with his new album, The Darkside. Comedian Chris Franjola, actress-comedian Arden Myrin and TV personality Ross Mathews

Eva Mendes

Episode number: 117

Overview: From The Other Guys, Eva Mendes is here. Comedian Dan Levy, comedian Natasha Leggero and comedian Ben Gleib.

Bethenny Frankel

Episode number: 118

Overview: Star of Bravo's Bethenny Getting Married?, Bethenny Frankel is here. Comedian Josh Wolf, comedian Whitney Cummings and comedian Guy Branum

Margaret Cho

Episode number: 119

Overview: Margaret Cho tells us about her new comedy/music album Cho Dependent. Comedian Heather McDonald, comedian Hyla Mathews and TV personality Ross Mathews.

Alanis Morissette

Episode number: 120

Overview: We're checking in with Alanis Morissette who's working her acting chops on the new season of Weeds. Comedian Bobby Lee, comedian Loni Love and comedian Dov Davidoff.

Extra Round Table

Episode number: 121

Overview: Extra Round Table. Comedian Jo Koy, comedian Sarah Colonna and comedian Jason Sklar

Kim Raver

Episode number: 122

Overview: Grey's Anatomy star Kim Raver tells us about her foray into the Lifetime TV movie, Bond of Silence. Comedian Finesse Mitchell, actress-comedian Arden Myrin, and TV personality Ross Mathews

Kim & Kourtney Kardashian

Episode number: 123

Overview: Kim and Kourtney Kardashian are here to make sure everyone is still Keeping Up With the Kardashians. Comedian Bill Bellamy, comedian Natasha Leggero and comedian Josh Wolf.

Jennifer Aniston

Episode number: 124

Overview: Jennifer Aniston is here telling us about her new film The Switch. Comedian John Caparulo, comedian Whitney Cummings and comedian Brad Wollack.

Elisabeth Shue

Episode number: 125

Overview: From the most frightening 3D movie of the summer, Piranha: 3D, Elisabeth Shue is here. Comedian Chris Franjola, comedian Owen Benjamin and comedian Jo Koy

Eli Roth

Episode number: 126

Overview: Eli Roth tells us about his latest film The Last Exorcism. Comedian Chris Hardwick, comedian Sarah Colonna and comedian Gary Valentine.

Rufus Wainwright

Episode number: 127

Overview: Rufus Wainwright tells us about his tour and latest CD, All Days are Nights: Songs for Lulu. Comedian Josh Wolf, comedian Heather McDonald and musician Jeff Wild.

Jerry Springer

Episode number: 128

Overview: Jerry Springer tells us about his foray into game shows as host of GSN's Baggage. Comedian Randy Sklar, comedian Christina Pazsitzky and comedian Guy Branum.

Angie Harmon

Episode number: 129

Overview: Angie Harmon tells us about her hugely popular show Rizzoli & Isles. Comedian Ben Gleib, comedian Godfrey and comedian Jo Koy

Jewel

Episode number: 130

Overview: Jewel returns and tells us about her new album, Sweet and Wild. Comedian Brad Wollack, comedian Natasha Leggero and comedian Steve Marmalstein.

Louise Roe

Episode number: 131

Overview: Host of CW's Plain Jane Louise Roe is here to make over the staff of Chelsea Lately. Comedian Josh Wolf, comedian John Caparulo and musician Jo Koy.

Extra Roundtable

Episode number: 132

Overview: You asked for more round table, tonight you're getting more round table. You're welcome, America. Comedian Chris Franjola, comedian Loni Love and comedian Joe DeRosa

Mel B

Episode number: 133

Overview: Mel B. tells us about her new Style Network show Mel B: It's a Scary Life. Comedian Greg Proops, actress-comedian Arden Myrin and comedian-host Rove McManus.

Ne-Yo

Episode number: 134

Overview: R&B singer Ne-Yo on his new album, "Libra Scale "; Round table discussion with comics Michael Yo, Jen Kirkman, and Ross Mathews.

B.o.B.

Episode number: 135

Overview: VMA performer and five-time nominee B.o.B is here with his No. 1 album B.o.B Presents: The Adventures of Bobby Ray. Comedian Matt Braunger, comedian Heather McDonald and comedian Josh Wolf.

Extra Roundtable

Episode number: 136

Overview: An extra-long Round Table. You're welcome, America. Comedian T. J. Miller, comedian Sarah Colonna and comedian Dov Davidoff.

Extra Roundtable

Episode number: 137

Overview: An extra-long Round Table. You're welcome, America. Comedian Ben Gleib, actress-comedian Whitney Cummings and comedian Jo Koy.

Emma Stone

Episode number: 138

Overview: From Easy A, the can-do-no-wrong-in-my-book Emma Stone is here. Comedian Chris Hardwick, actress-comedian Arden Myrin and comedian Kevin Hart.

Snooki and Pauly D

Episode number: 139

Overview: Get ready to GTL because Jersey Shore's Snooki and Pauly D are back. Comedian Donnell Rawlings, comedian Natasha Leggero and comedian Brad Wollack.

Usher

Episode number: 140

Overview: Usher has a new album, Versus, is on tour and is hanging out with us tonight, everyone rejoice. Comedian Loni Love, comedian Chris Franjola and musician Jeff Wild.

Jared Leto

Episode number: 141

Overview: Jared Leto, lead singer of the band '30 Seconds to Mars.' Comedian John Caparulo, comedian Guy Branum and comedian Lavell Crawford

Meghan McCain

Episode number: 142

Overview: We welcome author of Dirty Sexy Politics, Meghan McCain. Comedian Josh Wolf, comedian Heather McDonald and comedian Gary Valentine.

Emily Rose

Episode number: 143

Overview: Emily Rose from SyFy's Haven is here. Comedian Matt Braunger, comedian Sarah Colonna and comedian Mo Mandel.

Laird Hamilton

Episode number: 144

Overview: We're pretty stoked that world-renowned surfer Laird Hamilton returns tonight. Comedian Jason Sklar, comedian Michelle Collins and comedian Jo Koy.

Kristen Bell

Episode number: 145

Overview: From the hilarious movie You Again, Jersey Shore's No. 1 fan Kristen Bell is here. Comedian Bobby Lee, comedian Whitney Cummings and TV personality Ross Mathews.

Adam Levine

Episode number: 146

Overview: Adam Levine of Maroon 5 is here with their new album Hands All Over. Comedian Brad Wollack, comedian John Caparulo and writer Diablo Cody.

Taye Diggs

Episode number: 147

Overview: Star of Private Practice Taye Diggs is here…he may or may not be wearing a shirt. Comedian Jo Koy, comedian Dov Davidoff and comedian Natasha Leggero.

Dax Shepard

Episode number: 148

Overview: Parenthood's Dax Shepard is here to discuss many a things, one being his new film The Freebie. Comedian Chris Franjola, comedian Dan Levy and TV personality Ross Mathews.

AnnaLynne McCord

Episode number: 149

Overview: AnnaLynne McCord is here to give us the 411 on all things 90210. Comedian Chris Hardwick, comedian Ben Gleib and actress-comedian Arden Myrin.

Duane "Dog" Chapman, Beth Smith Chapman,

Episode number: 150

Overview: Dog the Bounty Hunter's Beth and Duane "Dog" Chapman grace our stage tonight. Comedian Moshe Kasher, comedian Heather McDonald and comedian Josh Wolf.

Tommy Lee

Episode number: 151

Overview: Tommy Lee is here with his latest Methods of Mayhem project A Public Disservice Announcement. TV personality Ross Mathews, comedian Whitney Cummings and comedian Guy Branum.

Kelly Osbourne

Episode number: 152

Overview: Cohost of E!'s Fashion Police, Kelly Osbourne, is here. Comedian Jo Koy, comedian Randy Sklar and comedian Loni Love.

Trace Adkins

Episode number: 153

Overview: The cowboy himself, Trace Adkins, is back with his new album Cowboy's Back in Town. Comedian Brad Wollack, comedian Chris Hardwick and comedian Natasha Leggero.

Leah Remini

Episode number: 154

Overview: Cohost of the new CBS talk show The Talk, Leah Remini is here. Comedian Jo Koy, comedian Sarah Colonna and comedian Greg Proops.

Lauren Conrad

Episode number: 155

Overview: Author of Sugar and Spice and Lauren Conrad Style the very busy Lauren Conrad is here. Comedian John Caparulo, comedian Josh Wolf and comedian Jim Breuer.

Amy Brenneman

Episode number: 156

Overview: From Private Practice, the delightful Amy Brenneman returns to the show tonight. Comedian Chris Franjola, actress-comedian Arden Myrin and comedian Kevin Hart.

Johnny Knoxville

Episode number: 157

Overview: The biggest jackass of them all, Johnny Knoxville from Jackass 3D is here. Comedian Ben Gleib, comedian Loni Love and TV personality Ross Mathews.

Blake Shelton

Episode number: 158

Overview: The newest member of the Grand Ole Opry, Blake Shelton is here with his new album All About Tonight. Comedian Jo Koy, comedian Heather McDonald and E!'s own Michael Yo.

Lloyd Banks

Episode number: 159

Overview: Rapper Lloyd Banks. Comedian John Caparulo, comedian Whitney Cummings and comedian Donnell Rawlings.

Jenny McCarthy

Episode number: 160

Overview: Jenny McCarthy is back with her latest book Love, Lust, and Faking It. Comedian Josh Wolf, musician Jeff Wild and comedian Guy Branum.

Julian McMahon

Episode number: 161

Overview: From the film Red Julian McMahon graces us with his presence tonight. Comedian Jo Koy, actress-comedian Arden Myrin, and TV personality Ross Mathews.

Milla Jovovich

Episode number: 162

Overview: Milla Jovovich returns to tell us about her new film Stone. Comedian Josh Wolf, comedian Chris Franjola and comedian Gary Valentine.

Jennifer Nettles

Episode number: 163

Overview: Jennifer Nettles of Sugarland returns tonight with their new album The Incredible Machine. Comedian John Caparulo, comedian Sarah Colonna and comedian Chris Hardwick.

Nick Swardson

Episode number: 164

Overview: From Nick Swardson's Pretend Time comedian Nick Swardson is here. Comedian Brad Wollack, comedian Michelle Collins and comedian Bobby Lee.

Eddie Izzard

Episode number: 165

Overview: Eddie Izzard from Showtime's United States of Tara is here. Comedian Jo Koy, comedian Natasha Leggero and comedian Ryan Stout.

Benji & Joel Madden

Episode number: 166

Overview: Benji and Joel Madden are here to tell us all about Good Charlotte's new album Cardiology. Comedian Josh Wolf, comedian Heather McDonald and comedian Bill Bellamy.

Emily Procter

Episode number: 167

Overview: Probably the most pregnant cast member of CSI: Miami, Emily Procter is here. Comedian Dan Levy, comedian Chris Franjola and comedian Sarah Colonna.

Connie Britton

Episode number: 168

Overview: From dare I say the greatest television show of all time (Friday Night Lights), we welcome Tami Taylor herself, the Emmy-nominated Connie Britton. Writer Diablo Cody, comedian Guy Branum and TV personality Ross Mathews.

Keenan Cahill

Episode number: 169

Overview: We've got YouTube sensation Keenan Cahill debuting his brand new video on the show tonight. Comedian Josh Wolf, comedian Chris Franjola and comedian Sarah Colonna

Kendra Wilkinson-Baskett

Episode number: 170

Overview: Kendra Wilkinson-Baskett is here to tell us all about the new season of her show Kendra. Comedian Jo Koy, comedian Matt Braunger and comedian Chris Hardwick

Starsky & Cox

Episode number: 171

Overview: Find out how all of the stars align tonight with cosmic astrologists Starsky and Cox. Comedian Loni Love, comedian John Caparulo and TV personality Ross Mathews

Florence Welch

Episode number: 172

Overview: Florence Welch, from one of this year's hottest acts, Florence + the Machine, is here. Comedian Jim Norton, comedian Brad Wollack and actress-comedian Arden Myrin

Monica Potter

Episode number: 173

Overview: From one of the best shows on TV, Parenthood, Monica Potter is here. Comedian Josh Wolf, comedian Natasha Leggero and comedian Greg Proops

Trey Songz

Episode number: 174

Overview: Trey Songz is bringing his Passion Pain and Pleasure (also the name of his new CD) to the show tonight, word. Comedian Jo Koy, comedian Heather McDonald and comedian T.J. Miller

Tom Bergeron

Episode number: 175

Overview: Dancing With the Stars' extraordinary host and Deb's BFF (sorry, Gary) Tom Bergeron is here. Comedian Dan Levy, comedian Sarah Colonna and comedian Gary Valentine

Nelly

Episode number: 176

Overview: Nelly is dropping by with his new album 5.0. This is for real, this is not just a dream...nailed it. Comedian Chris Franjola, E! News correspondent Michael Yo and TV personality Ross Mathews

Single security guards

Episode number: 177

Overview: It's the return of Single Staffers...just in time for the holiday season, you're welcome America! Comedian John Caparulo, actress-Comedian Arden Myrin and comedian Ryan Stout.

Dane Cook

Episode number: 178

Overview: Dane Cook is here with his greatest hits album, I Did My Best. Comedian Jo Koy, comedian Kevin Hart and comedian Ben Gleib

Taylor Swift

Episode number: 179

Overview: Taylor Swift has a new album, called Speak Now, and she's here to tell us all about it. Topless comedian Brad Wollack, comedian Loni Love and comedian Gary Valentine

Donald Schultz

Episode number: 180

Overview: Animal expert Donald Schultz is here with an alligator, a prairie dog and a rattlesnake. Comedian Bobby Lee, comedian Whitney Cummings and TV personality Ross Mathews

John Stamos

Episode number: 181

Overview: One of the greatest gifts television has ever given us, John Stamos who's been guesting on Glee is here. Comedian Josh Wolf, comedian Heather McDonald and TV personality Ross Mathews

Flo Rida

Episode number: 182

Overview: Flo Rida is here with his new album Only 1 Flo and hopefully some explanation for the state of Florida. Comedian Jo Koy, comedian Sarah Colonna and comedian Mo Mandel

Cee-Lo Green

Episode number: 183

Overview: Tonight we welcome The Lady Killer himself Cee-Lo Green. Topless Comedian Chris Hardwick, comedian Natasha Leggero and comedian Chris Franjola

Kate Bosworth

Episode number: 184

Overview: From the new film The Warrior's Way Kate Bosworth is here. Comedian John Caparulo, comedian Matt Braunger and writer Diablo Cody