Overview: American gun owners shoot their penises off at an alarming rate, and Larry examines Jeb Bush's comments about black voters with DeRay Mckesson, Mike Yard and Rory Albanese.
Overview: President Obama and Vladimir Putin face off at the U.N. summit, and Larry discusses the discovery of water on Mars with Bill Nye, Michelle Buteau and Ricky Velez.
Overview: Congressional Republicans attack Planned Parenthood President Cecile Richards, and Larry discusses Donald Trump's tax plan with Robert Reich, Marina Franklin and Mike Yard.
Overview: Donald Trump faces fraud allegations from students of Trump University, and Larry discusses Russia's bombing campaign in Syria with Eddie Huang, Lisa Ling and Jordan Carlos.
Overview: Larry revisits his interview with presidential hopeful Bernie Sanders, and Rory Albanese, Mike Yard and Ashleigh Banfield weigh in on a mass shooting at an Oregon college.
Overview: Larry examines Hillary Clinton's public image, and Jessica Kirson, John Avlon and Joey Bada$$ talk about what qualities appeal to them in a presidential candidate.
Overview: California enacts a landmark death-with-dignity law, and Jay Leno, Bobby Gaylor and Michelle Collins discuss Ben Carson's surprising reaction to a mass shooting.
Overview: President Obama apologizes after American forces bomb a Doctors Without Borders hospital, and Rupert Murdoch tweets his support of Ben Carson's presidential campaign.
Overview: Nancy Pelosi joins Larry for an enlightening ice cream social, and Mike Yard, James Davis and Jeezy debate Barack Obama's legacy as America's first black president.
Overview: A toy pirate ship comes with a slave figurine, and Larry chats about the popularity of Donald Trump and Bernie Sanders with Jesse Ventura, Seaton Smith and Kathleen Madigan.
Overview: Larry examines the highs and lows of the first 2016 Democratic presidential debate with Steve Kornacki, Rory Albanese and Gabrielle Union.
Overview: Police officers gripe about being filmed by the public, and Larry discusses Jennifer Lawrence's essay on the gender pay gap with Grace Parra, Raul De Molina and Holly Walker.
Overview: Donald Trump spars with Jeb Bush over 9/11, Larry discusses Operation GroupMe with Raury, Mike Yard and Natasha Rothwell, and Raury performs a song from "All We Need."
Overview: American toddlers shoot people on a weekly basis, and Larry discusses wealth therapy for the beleaguered rich with Jeff Daniels, Rachel Feinstein and Joe Budden.
Overview: The CIA chief falls prey to hackers, and Larry discusses Joe Biden's announcement that he won't be running for president with Holly Walker, Ryan Duffy and Terry Crews.
Overview: A rash of fires plague black churches in Ferguson, Mo., and Larry discusses Rep. Paul Ryan's family leave demands with Lucy Lawless, Bonnie McFarlane and Judah Friedlander.
Overview: GOP presidential hopeful Rand Paul chats about Donald Trump over soul food, and Bob Saget, Ana Kasparian and Mike Yard discuss cringe-worthy Halloween costumes.
Overview: Republicans try to seize control of the presidential debates, and Larry discusses Ben Carson's unlikely political success with Ron Perlman, Crystal Wright and Jordan Carlos.
Overview: Ohio citizens vote against legalizing marijuana, and Larry discusses the clash between religion and science with Neil deGrasse Tyson, Tom Papa and Carl Lentz.
Overview: GOP presidential candidate Ben Carson releases a cringeworthy rap song, and Larry examines celebrity activism with Lola Ogunnaike, Niecy Nash and Bobby Gaylor.
Overview: Ricky Velez takes on racism in wrestling, and Larry discusses a study that claims all women are either bisexual or gay with Alex Berg, Mike Yard and Grace Parra.
Overview: Ricky Velez throws down with former WWE wrestler Virgil, and Larry discusses solutions to global warming with Bill Nye, Bridget Everett and Rory Albanese.
Overview: Shonda Rhimes discusses her memoir "Year of Yes," and Larry examines failing GOP presidential campaigns with Franchesca Ramsey, Steve Kornacki and Jordan Carlos.
Overview: A Starbucks holiday cup incurs the wrath of conservative Christians, and Larry grapples with the morals of killing baby Hitler with Norman Lear, Bill Engvall and Rick Ross.
Overview: Bernie Sanders and Hillary Clinton make waves at the second Democratic debate, and Larry discusses the term "radical Islam" with Dean Obeidallah, John Avlon and John Green.
Overview: Republicans take a hard stance against Syrian refugees, and Larry examines the rise in anti-racism protests on college campuses with Jonathan Butler, Jadakiss and Grace Parra.
Overview: Ben Carson releases a bungled map of the U.S., and Larry talks emoji etiquette with Ty Dolla $ign, Robin Thede and Rory Albanese.
Overview: Mike Yard goes head to head with the NHL's Cal Clutterbuck, and Larry gears up for Thanksgiving with Sway Calloway, Mike Yard and Holly Walker.
Overview: Fox News's Brian Kilmeade brings up a racist stereotype, and Larry discusses the Planned Parenthood shooting in Colorado with Busta Rhymes, Jordan Carlos and Grace Parra.
Overview: The Texas school board takes a red pen to American history, and Larry discusses the source of Donald Trump's popularity with Pete Wentz, Ricky Velez and Holly Walker.
Overview: Chicago Mayor Rahm Emanuel fires his police chief over the shooting death of a black teen, and Larry discusses colorblind casting with Spike Lee, Rory Albanese and Mike Yard.
Overview: Gun massacres become an American institution, and Larry discusses questionable names for babies with Brian Posehn, Bobby Gaylor and Robin Thede.
Overview: President Obama awkwardly attempts to calm America's fears about ISIS, and Larry discusses pandering politicians with Jon Glaser, Rory Albanese and Mike Yard.
Overview: The leader of ISIS becomes a finalist for TIME's Person of the Year, and Larry discusses Donald Trump's anti-Muslim campaign with Mark Cuban, Jordan Carlos and Grace Parra.
Overview: A toxic blanket of smog envelops Beijing, and Larry examines the pros and cons of social media with Q, Rory Albanese and Robin Thede.
Overview: A white student sues the University of Texas over affirmative action, and Larry discusses Donald Trump's soaring poll numbers with Kevin Nealon, Grace Parra and Mike Yard.
Overview: A South Carolina lawmaker's Christmas card features the Confederate flag, and Larry examines Ted Cruz's surge in GOP polls with Aida Rodriguez, Jordan Carlos and Mike Yard.
Overview: Bill Cosby sues seven of his accusers for defamation, and Larry discusses a historically realistic portrait of Jesus Christ with Taye Diggs, Rory Albanese and Robin Thede.
Overview: Republican presidential hopefuls debate foreign policy, and Larry discusses Serena Williams's Sportsperson of the Year award with T-Pain, Holly Walker and Grace Parra.
Overview: An infamous pharma CEO is arrested on fraud charges, and Larry revisits some of the most significant stories of 2015 with Pusha T, Rory Albanese and Mike Yard.
Overview: An armed militia group occupies a federal wildlife refuge in Oregon, and Larry discusses the arrest of Bill Cosby with Franchesca Ramsey, Mike Yard and Holly Walker.
Overview: Donald Trump blasts Hillary Clinton for using the bathroom, and Bernie Sanders discusses his presidential candidacy with Larry, Grace Parra and Jordan Carlos.
Overview: Critics slam the president for shedding tears during a speech on gun control, and Larry examines the media's role in violence with Wesley Morris, Ricky Velez and Robin Thede.