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Pilot
Episode number: 1
Overview: A new patient who is in critical need of a heart transplanthas to rely on Dr. Panttiere and the unconventional methods she uses.
Twins
Episode number: 2
Overview: An ethical debate begins after Alex suggests performing some risky surgery on conjoined twins that have been diagnosed with cancer.
Backwards
Episode number: 3
Overview: Alex sees a young man who is only able to recite sentences backward as a chance to try out some new technology.
100,000 Heartbeats
Episode number: 4
Overview: Alex and Pierce are at odds about whether the hospital should provide an experimental treatment for patients with advanced-stage cancer. In other events, Max wants to change the family dynamic with Alex and Ji Sung connects with Callahan.
The Land of Normal
Episode number: 5
Overview: A patient questions Alex's ability to leave personal grief outside the OR when she performs heart surgery on the anniversary of her sister's death; Millicent dates an artist; Pierce wants to be more of a part of Alex's family.
The Inverse
Episode number: 6
Overview: A case brings back memories for Alex, Jesse and Millicent as they fight to save a heart transplant patient when she sustains devastating injuries in a car crash.
Permanent Glitter
Episode number: 7
Overview: Alex and Ji-Sung fight to save the life of a transgender woman with breast cancer; a consultant from another hospital forces Jesse to confront her feelings for Alex.
Match Game
Episode number: 8
Overview: When Alex's father needs a new kidney, an unlikely donor emerges and family secrets threaten to destroy the close relationship between father and daughter.
Sanctuary
Episode number: 9
Overview: Alex (Melissa George) and Jesse (Don Hany) put the hospital's reputation on the line while trying to fulfill the dying wish of a young heart patient.
What Happens in Vegas... Happens
Episode number: 10
Overview: In the Season 1 finale, a mysterious illness sends the hospital into lockdown; and leaves Alex fighting to save the lives of Jesse, Pierce and Ji-Sung. In other events, Millicent deals with the consequences when Alex disobeys the CDC; and an elderly man's search for his missing wife causes Alex to make a major decision about her love life.