Overview: Chelsea kicks off a whole new journey of discovery and delinquency with guests Drew Barrymore, Chris Martin and the U.S. secretary of education.
Overview: Chelsea talks lube with Gwyneth Paltrow and lobbying with Tony Hale, tests her acting chops in a telenovela, and learns the secret to an ace TED talk.
Overview: Chris Evans and the "Civil War" cast dish on superhero culture and Hollywood's blind spots, and Chadwick Boseman schools Chelsea on Black Panther.
Overview: Chelsea talks tour life with Gwen Stefani, steps out with a colorful Harajuku squad, and studies the moon with NASA's "Mohawk Guy," Bobak Ferdowsi.
Overview: Chelsea delves into the U.S. presidential race with comedian Wanda Sykes, former Obama speechwriter Jon Favreau and a posse of senior Florida voters.
Overview: Chelsea reaches for a big note with the Grammy-winning "Voice" coach and steps into the rink with a pair of Russian figure skaters.
Overview: Senator Boxer and African-American churchgoers break down what's at stake in the 2016 election. Snapchat guru DJ Khaled preaches the keys to success.
Overview: Recovering addicts warn of porn's troubling side effects, and the "Crazy Ex-Girlfriend" star charts her journey from despair to a Golden Globe.
Overview: The actor-turned-mogul shares investing tips and joins Cindy McCain to shed light on human trafficking. Chelsea steps out as a dog walker for hire.
Overview: Avowed non-parent Chelsea grills Kate Hudson and others about the appeal of raising kids and has her nails done by a gender-nonconforming 9-year-old.
Overview: The Science Guy weighs in on Chelsea's cryotherapy experiment and his new thinking on GMOs. "Masters of Sex" star Lizzy Caplan performs a magic trick.
Overview: MSNBC's Jacob Soboroff explains the fuss over superdelegates, and astrology maven Megan Fox tries to make sense of mixed signals in Chelsea's chart.
Overview: Chelsea dives into a grueling mud race, Will Arnett puts a new spin on Trump's tweets, and "Daily Show" Hasan Minhaj talks Indian toilets.
Overview: Chelsea talks threesomes with the 'Do-Over' star, waits tables with her niece, and gets the inside scoop on Melissa Arnot's historic Everest feat.
Overview: The rapper joins California Lt. Governor Gavin Newsom to push for game-changing action on pot. Chelsea tries working out stoned with an MMA fighter.
Overview: Chelsea delves into the world of "Narcos" with star Wagner Moura and real-life DEA agent Javier Peña. Ariana Huffington warns of sleeping pill risks.
Overview: The actress opens up about her LGBT travel show and the devastating toll of the Orlando shooting. Also featuring Florence Henderson, Von Miller.
Overview: Chelsea gives Mexican teens a whack at Donald Trump, while Keith Olbermann sizes up the candidate's psyche. Anna Faris and Allison Janney talk Kegels.
Overview: "People v. O.J." star Sarah Paulson praises Marcia Clark. Nancy Pelosi calls for action on guns. Jason Biggs and Jenny Mollen share wild travel tales.
Overview: "Walking Dead" star Norman Reedus gives Chelsea a taste of motorcycle culture. Strahan talks flirting, good fortune and his new underwear line.
Overview: Comedians Adam Devine and Maria Bamford talk stand-ups, psych wards and success. Chelsea tries a mindful coloring session with Metta World Peace.
Overview: The actress details a hair-raising outing in Hawaii. Comedian Jim Gaffigan responds to the backlash over his manicure tweet. Plus, modern dating tips.
Overview: The country star reveals how girlfriend Gwen Stefani upstaged him on his birthday. Former congressman Barney Frank shares his ideal Democratic ticket.
Overview: Alexander Skarsgård reveals his punishing 'Legend of Tarzan' diet, Aubrey Plaza fantasizes about freeing dolphins, and Chelsea studies the red planet.
Overview: Chelsea sips mezcal with actor Diego Luna, gets a history lesson from Eva Longoria and grills former Mexican president Fox on bullfighting and Trump.
Overview: The 'Mad Max' star opens up about her nontraditional family and dream of stamping out HIV. Jacob Soboroff sizes up VP rumors ahead of the RNC and DNC.
Overview: The 'Real Time' host rips into Donald Trump, a former top cop talks police militarization, and Olympian Tony Azevedo reveals racy water polo secrets.
Overview: The 'Glee' and '#RichKids' stars talk coming out, gay bars and evolving labels. A transgender woman and her partner share their transitioning story.
Overview: The actress responds to 'Ghostbusters' skeptics and flouts fashion norms with her new clothing line. Zachary Quinto celebrates a 'Star Trek' first.
Overview: 'Suicide Squad' star Adewale Akinnuoye-Agbaje and chef Gordon Ramsay break down Britain's predicament. 'Tickled' lifts the lid on a surreal world.
Overview: NeNe Leakes, Clay Aiken and fellow "Celebrity Apprentice" alums dissect the GOP nominee's appeal. Comedian Jim Jefferies poses with male strippers.
Overview: Chelsea rents her house out to a Filipino family on Airbnb, Jay Leno relives a hairy crash, and actress Gillian Jacobs shares a terror of improv.
Overview: The 'Orphan Black' star shares the secret to playing clones. The Go-Go's reflect on 38 years of fun, fame and fistfights ahead of their farewell tour.
Overview: Reese Witherspoon, Common and friends of different faiths open up about their spiritual journeys. Chelsea gets a crash course in religious history.
Overview: Emotions run high as Chelsea crashes her first political convention and learns about a civil rights hero. With Jacob Soboroff and David Axelrod.
Overview: Jason Biggs hops into the pool with the U.S. men's Olympic water polo team. The irrepressible Denis Leary riffs on his wild past and 27-year marriage.
Overview: Chelsea's niece steps in as co-host, and Bryce Dallas Howard offers tips on growing up in a famous family. James Carville marvels at Trump's behavior.
Overview: Mayor Aja Brown fights to rebuild a city plagued by turmoil. David Axelrod offers insights on Obama. Michael Kelly talks eerie 'House of Cards' plots.
Overview: In the land of vodka, Chelsea braves a bracing spa ritual, tries rhythmic gymnastics with Maria Sharapova and probes the mystery of Russian men.
Overview: Chelsea gets sex tips from an adult film icon, talks history with 'Ben-Hur' star Jack Huston and urges the 'American Ninja Warrior' hosts to man up.
Overview: The actress reflects on her complex relationship with social media after the death of her father, Robin. Plus, Jon Favreau on Obama's writing habits.
Overview: Chelsea asks Tinder CEO Sean Rad for help with her profile and heads into the wilderness for survival school. With Eric André and Joel Kinnaman.
Overview: Sparks fly as Chelsea talks cats, fame and Obama with comedian Marc Maron and actress Natasha Lyonne. Plus, Olympic swimming champ Nathan Adrian.
Overview: Kate Upton and a crew of YouTube stars discuss the life-changing power of social media. Nasty Gal's Sophia Amoruso shares her wild success story.
Overview: Model Ashley Graham and country singer Jana Kramer bond over their brushes with public shaming. Plus, beauty pageant boot camp and comic Jimmy Carr.
Overview: Hasan Minhaj of "The Daily Show" recounts his hair-raising trip to the RNC, and the women of "Mr. Robot" celebrate their stereotype-defying roles.
Overview: "New Girl" star Max Greenfield hails the joys of fantasy football, Noah Galloway discusses his post-"DWTS" breakup, and Jeff Ross roasts Ann Coulter.
Overview: Comedian David Cross mourns the "quaint" early stages of Trump's campaign. Chelsea and "Sully" actor Aaron Eckhart talk phobias and hypnosis.
Overview: Chelsea invites a politically diverse group including W. Kamau Bell and S.E. Cupp to dissect the rise of Trump and the issues that divide Americans.
Overview: The kids from "Stranger Things" talk sudden fame and welcome a surprise visitor. Abigail Breslin slams an offensive tweet. Plus, comedian Bob Saget.
Overview: Oscar winner Patricia Arquette makes an urgent plea for equal pay, and Aisha Tyler rejects the toxic female relationships depicted on TV.
Overview: Neil deGrasse Tyson explains the hazards of zero-gravity intimacy. Michael Sheen talks "Masters of Sex." Jenny Mollen obsesses over Jason Biggs's ex.
Overview: Sarah Silverman opens up about a recent health scare and her fiery DNC remarks. Gloria Steinem talks politics and her Emmy-nominated Vice show.
Overview: "OITNB" actress Diane Guerrero reflects on her parents' deportation. Mike Colter shares the symbolism behind Luke Cage's hoodie. With Craig Ferguson.
Overview: "Bridget Jones" star Renée Zellweger looks back on a life-changing phone call. Chris Geere recalls an awkward sex scene. Plus: Who is Alex Trebek?
Overview: Amy Schumer riffs on awkward family dynamics, dating life and pressure from fans. "Shark Tank" star Mark Cuban explains his change of heart on Trump.
Overview: Chris Pratt and his "Magnificent Seven" posse talk feisty horses and behind-the-scenes bromance. Chelsea heads to the racetrack for jockey school.
Overview: Lea Michele's tales of stripping down take even Chelsea by surprise. NBA Hall of Famer Reggie Miller salutes Colin Kaepernick. With comic T.J. Miller.
Overview: "Girl on the Train" actor Edgar Ramírez rips harmful gender stereotypes. Jessica Alba shares the key to her Honest Company success. With Gavin Newsom.
Overview: Chelsea taps the conservative pundit's "body double" for a biting interview. Kristen Bell finds a cure for online gloom and doom. With Jacob Soboroff.
Overview: Don Cheadle, Joshua Jackson, Ed Begley Jr. and the U.S. secretary of energy delve into the dangers we're facing and steps everyone can take to help.
Overview: Rob Lowe dishes on his brutal Comedy Central roast and life as a Hollywood heartthrob. With comedians Nick Kroll, John Mulaney and Russell Peters.
Overview: Krysten Ritter hails the cliché-crushing power of Jessica Jones. Rumer Willis pushes back on doctored photos. Plus, the inside story of "Amanda Knox."
Overview: Chelsea's bid to become a Lyft driver turns tense when she takes her mentor on a hair-raising ride. With Taylor Lautner and the Property Brothers.
Overview: Education Secretary John King quizzes Chelsea on geography and more. Glennon Doyle Melton calls out toxic messages to girls. Plus, Jennifer Connelly.
Overview: Comedian Kevin Hart talks fame, marriage and the mistakes of his past. Jesse Ventura slams the "rigged" election. Larry King moderates a mock debate.
Overview: Chelsea sits down with Hilary Swank, Ava DuVernay, Connie Britton and the reigning Miss USA to talk ambition, sexuality, burning injustices and more.
Overview: Tyler Perry reflects on a wild twist of fate, his foray into fatherhood and buying an Army base. With Cobie Smulders and Vice's Alyssa Mastromonaco.
Overview: Jason Biggs and Jenny Mollen go to work for Team Clinton. Journalist Jorge Ramos warns of a rising tide of hatred. With Isla Fisher and Thomas Lennon.
Overview: Grammy winner Meghan Trainor dishes on her new beau, her creative process and more. Plus, Priyanka Chopra and transgender Senate hopeful Misty Snow.
Overview: Felicity Jones and Ron Howard talk "Inferno," awkward auditions and the closely guarded secrets of "Rogue One." Norah Jones hits the stage to perform.
Overview: Shannen Doherty offers a raw glimpse of how cancer has redefined her self-image, upended long relationships and changed her life -- for the better.
Overview: Nicole Richie opens up about her transformation from rebellious youth to poised mom and women's advocate. Plus, "Moonlight" star Trevante Rhodes.
Overview: Chelsea Clinton speaks out about her mother's resilience, the high stakes in this election, and an "offensive" ploy by Trump. With Rose McGowan.
Overview: Stella and Mary McCartney talk fashion, royalty and sisterhood. Craig Ferguson offers a primer on Scotland. Plus, Colleen Ballinger and Kimbal Musk.
Overview: Comedy legend Carol Burnett shares the joys and hazards of hosting her own variety show in the 1960s. With Rob Corddry and ESPN's Jessica Mendoza.
Overview: Chelsea sifts through the dizzying emotional and political fallout of the election with help from Sen. Barbara Boxer, Mary McCormack and Nikki Glaser.
Overview: Sarah Jessica Parker, Morgan Spurlock, Trevor Noah and Julianna Margulies talk friends, parenting, work and the bonds that have shaped their lives.
Overview: Jake Tapper weighs in on Donald Trump's shifting positions, Maria Shriver critiques Chelsea's interviewing style, and Matt LeBlanc talks "Top Gear."
Overview: Emmy Rossum recounts a bold career move, Obama adviser Valerie Jarrett looks back on the president's big wins, and Flula explores the world of D&D.
Overview: Chelsea grills Milo Ventimiglia on the "Gilmore Girls" revival and his "This Is Us" physique. Kyra Sedgwick reflects on her 28-year marriage.
Overview: Chelsea heads to Japan to play drinking games with geishas, visit cat cafés and crying clinics, and interrogate the locals on dating, sex and more.
Overview: Sally Field offers a defiant response to Trump's victory. Jacob Soboroff explains the recount process. Plus, Jason Biggs and a tribute to Mrs. Brady.
Overview: Jessica Chastain shares her grandmother's saucy advice, Chelsea makes a bet with Dale Earnhardt Jr., and Van Jones rebukes Democrats and Republicans.
Overview: Stars of "Orange Is the New Black" reflect on how the show has changed their lives -- and the world. Four women share their real-life prison stories.
Overview: Susan Sarandon breaks down the dramatic Dakota pipeline standoff and the #BankExit push. Gael García Bernal extols the pleasures of mezcal and Venice.
Overview: Jennifer Aniston talks "Office Christmas Party" and her ideal superhero role. Fetty Wap explains his stance on guns. Chelsea gets high with her staff.
Overview: Kate Hudson recalls a magical holiday, LA Mayor Eric Garcetti shares his plea to Donald Trump, and Cameron Dallas and friends talk social media fame.
Overview: Common looks back on Obama's impact, country star Maren Morris marvels at her wild year, and journalist Lauren Duca dissects lies by Trump.
Overview: In the season finale, Oscar winner Jennifer Lawrence gets punchy, Chris Hardwick talks zombies, and Chelsea revisits favorite moments from the show.